Abstract

This research purpose is to estimate the dose distribution of BNCT in water phantom. Some common methods in the treatment of cancer such as brakhiterapi, surgery, chemotherapy, and radiotherapy still have the risk of damaging healthy tissue around cancer cells. BNCT is a selectively-designed technique by targeting high-loaded LET particles to tumors at the cellular level. BNCT proves to be a powerful method of killing cancer without damaging normal tissue. The source of the neutron used from the cyclotron dose in water phantom with the size of 30 cm x 30 cm x 30 cm was calculated using PHITS program. The result from the simulation is that boron water panthom has a dosimetri higher than phantom water without boron.

Highlights

  • WHO released data showing in 2015 as many as 8.8 million people died from cancer, with details of lung cancer (1.69 million deaths), liver (788,000 deaths), colorectal (774,000 deaths), stomach (754,000 deaths), and Breast cancer (571,000 deaths)

  • Cervical cancer and breast cancer is the highest prevalence of cancer in Indonesia in 2013, which amounted to 0.8 ‰ of cervical cancer and breast cancer of 0.5 ‰

  • The purpose of this research is to estimate the spread of the dose of proton, nitrogen, boron and photon in water phantom with source of neutron from cyclotron where the distribution of dose in water phantom is known and simulated using tally program Particle and Heavy Ion Transport Simulation (PHITS)

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Summary

Introduction

WHO released data showing in 2015 as many as 8.8 million people died from cancer, with details of lung cancer (1.69 million deaths), liver (788,000 deaths), colorectal (774,000 deaths), stomach (754,000 deaths), and Breast cancer (571,000 deaths). That number makes cancer a major cause of both global deaths [1]. According to data from the Ministry of Health of Indonesia in 2013, the prevalence of cancer in the population of all ages in Indonesia is 1.4 ‰ or estimated to be around 347 792 people. Based on an estimated number of cancer patients of Central Java Province and East Java Province is province with estimation of cancer patient mostly, that is about 68.638 and 61.230 people[2]

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