Distribution of pathogens and drug resistance of puerperal infection in 41 twin pregnancies

Abstract

Objective The distribution and drug resistance of pathogenic bacteria of the twin pregnancy with puerperal infection were analyzed. Methods 41 twin pregnancy cases with puerperal infection were screened out and the clinical data were retrospectively analyzed. Results A total of 48 main pathogenic bacteria were detected, including 21 Gram-positive bacteria: 9 Staphylococcus aureus (18.8%), 7 Streptococcus hemolyticus (14.6%) and 5 Enterococcus faecalis (10.4%); 27 Gram-negative bacteria: 12 Escherichia coli (25.0%), 8 Aerogenic Enterobacter (16.7%) and 7 Gardnerella vaginalis (14.6%). Drug resistance: 3 kinds of Gram-positive bacteria were strongly resistant to ceftazidime, and were sensitive to piperacillin sulbactam. Staphylococcus aureus and Streptococcus hemolytic streptococcus were sensitive to clindamycin, and Enterococcus faecalis was strongly resistant to penicillin. 3 kinds of Gram-negative bacteria were sensitive to gentamicin and were strongly resistant to ampicillin and cefazolin. Escherichia coli and Enterobacteriaceae were sensitive to cefepime, and Gardnerella vaginalis were sensitive to levofloxacin, and were strongly resistant to cefepime. The main pathogenic bacteria were sensitive to meropenem and vancomycin. Conclusions According to the distribution and drug resistance of pathogens, we should rationally choose antimicrobial agents to prevent and cure puerperal infection of twin pregnancy. Key words: Twins; Puerperal infection/MI; Microbial sensitivity tests; Drug resistance, bacterial