Abstract
Hypothesis/aims of study. The current analysis was undertaken to assess the incidence of malignant diseases in patients with endometriosis.
 Study design, materials and methods. This is a cohort study of women with surgically verified endometriosis retrieved from the Saint Petersburg 122 Clinical Hospital Discharge Register 1996–2006 (n = 1551). Data were linked to the Saint Petersburg Cancer Agency to identify cases of malignancy.
 Results. Malignant diseases were identified in 6.3% (n = 98) of cases. The median follow-up was 12.2 (7.5) years. Breast cancer (n = 29), ovarian cancer (n = 7), endometrial cancer (n = 7), thyroid cancer (n = 7), colorectal cancer (n = 6), melanoma (n = 6), non-Hodgkin’s lymphoma (n = 4), and glioblastoma (n = 3) were prevalent.
 Conclusion. The incidence of cancer in patients with endometriosis is low. Women with endometriosis have an increased risk of some malignancies, particularly ovarian cancer.
Highlights
■ Цель — оценить заболеваемость злокачественными новообразованиями (ЗНО) у больных эндометриозом
The current analysis was undertaken to assess the incidence of malignant diseases in patients with endometriosis
This is a cohort study of women with surgically verified endometriosis retrieved from the Saint Petersburg 122 Clinical Hospital Discharge Register 1996–2006 (n = 1551)
Summary
Для цитирования: Байрамова Н.Н., Протасова А.Э., Раскин Г.А., и др. ■ Цель — оценить заболеваемость злокачественными новообразованиями (ЗНО) у больных эндометриозом. В структуре анализируемой группы в 98 случаях выявлены ЗНО, что составило 6,3 %. Средний период наблюдения женщин с момента постановки диагноза эндометриоза до возникновения ЗНО — 12,2 (7,5) года. В структуре выявленных ЗНО преобладали: рак молочной железы (n = 29), рак яичника (n = 7), рак тела матки (n = 7), рак щитовидной железы (n = 7) и колоректальный рак (n = 6), а также кожная меланома (n = 6), неходжкинская лимфома (n = 4) и глиобластома (n = 3). Результаты исследования показывают, что частота малигнизации эндометриоза крайне низка и у женщин с эндометриозом прослеживается тенденция к увеличению заболеваемости лишь некоторыми злокачественными новообразованиями, в особенности раком яичника.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
