Abstract
Distribution of allelic variants of a poly-adenine tract microsatellite named BAT-40, locating at intron 2 of 3-beta-hydroxysteroid dehydrogenase gene, were investigated in 412 Japanese individuals free from mismatch repair gene defect. Out of them, 60 (14.6%) were heterozygotes for BAT-40, which is significantly lower than that reported in Europeans. Observed allelic variants in the Japanese ranged from 17- to 46-adenine repeats with different distribution pattern from those reported in the Americans or Europeans. These data will provide significant background knowledge for the evaluation of microsatellite instability in cancer DNA from the Japanese population.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
