Abstract
Diabetes is growing as an epidemic, with around 250 million diabetics estimated globally and which is expected to rise up to 380 million in the next 15 years. Differences in the efficacy and toxicity of various antidiabetic drugs have been linked to polymorphisms in various drug metabolizing enzymes. In this study we have investigated the frequency of occurrence of two single nucleotide polymorphisms in the CYP gene (CYP2C8*3 and CYP2C9*2) in type 2 diabetes mellitus (T2DM) patients from North India.
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