Abstract

Psoriasis is a chronic inflammatory systemic disorder that associates many cardiovascular comorbidities. The association between psoriasis and cardiovascular disease is a complex one, which implies many risk factors, such as age, gender, heredity, smoking, alcohol and stress. The prognosis of patients with psoriasis may be improved by identifying and reduction of these cardiovascular risk factors. The objective of our study was to determine the prevalence of cardiovascular risk factors among patients with psoriasis from Bucharest and Ilfov county, Romania. 634 individuals from the general population were initially included. From these individuals, 208 patients with psoriasis have been selected for inclusion in our observational study. The patients were selected from Elias Emergency Hospital of Bucharest, Romania, and through the family doctors praxis, between 2010-2017. Of the 634 individuals from the general population, 208 patients (33%) were identified as patients with a diagnosis of vulgar psoriasis, confirmed by the dermatologist, forming the study group. The presence of risk factors is consistent with the presence of cardiovascular disease (23%) in the studied group. Patients with psoriasis, without cardiovascular diseases, have an increased risk of developing them throughout their lives. Patients with psoriasis have a very high risk of developing life-long cardiovascular disease, because of a multitude of risk factors associated with psoriasis. Intervention on modifiable risk factors for cardiovascular disease can be mediated by a family doctor, who can monitor the development over time and may also intervene early when appropriate.

Highlights

  • Psoriasis is a chronic inflammatory systemic disorder that associates many cardiovascular comorbidities

  • Psoriasis is a systemic chronic inflammatory disease associated with several comorbidities: cardiovascular disease, metabolic syndrome, diabetes, obesity, dyslipidemia [7,8]

  • The distribution of cardiovascular risk factors in patients with psoriasis must be evaluated, in order to determine the risk of cardiovascular disease and to apply preventive strategies

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Summary

Distribution of Cardiovascular Risk Factors in Patients with Psoriasis

ANA MARIA ALEXANDRA STANESCU1*, IOANA VERONICA GRAJDEANU1, BOGDAN SERBAN12, CAMELIA CRISTINA DIACONU1,3 1University of Medicine and Pharmacy Carol Davila, 8 Eroii Sanitari Str, Bucharest, 050474, Bucharest, Romania 2Emergency University Hospital Bucharest, 169 Splaiul Independentei, 050098, Bucharest, Romania 3Clinical Emergency Hospital of Bucharest, 8 Calea Floreasca, 014461, Bucharest, Romania. The association between psoriasis and cardiovascular disease is a complex one, which implies many risk factors, such as age, gender, heredity, smoking, alcohol and stress. The objective of our study was to determine the prevalence of cardiovascular risk factors among patients with psoriasis from Bucharest and Ilfov county, Romania. The prevalence of psoriasis varies by country, varying between 0.09% and 11.4% [1,2] The death of these patients generally does not occur because of psoriasis, but rather because of associated co-morbidities, especially cardiovascular events [3,4,5]. The objective of our study was to determine the prevalence of cardiovascular risk factors among patients with psoriasis from Bucharest and Ilfov county

Experimental part Materials and method
Results and discussions
Conclusions

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