Abstract
Background: Attempts being made to unravel the relationship between blood antigens, hemoglobin (Hb) genotypes and increased susceptibility to certain diseases are ongoing. Objective: The study was carried out to provide data on the distribution of ABO, Rh D, and Hb variants among pregnant women receiving antenatal care at Federal Medical Centre, Yola, Nigeria. Materials and Methods: Medical records of these subjects (n = 2226) were sorted out and analyzed according to their ABO blood group phenotypes and Hb variants. Results: Blood group O was the most prevalent (47.7%) among our subjects, followed by A (26.6%), B (22.2%), and AB (3.5%). The Rh D antigen was positive in 97.1% and negative in 2.9% of the study population. There were five Hb genotypes AA (81.94%), AC (0.34%), AS (17.57%), SC (0.05%), and SS (0.14%). The occurrence of different ABO, Rh D blood groups and Hb variants varied significantly (P Conclusion: The frequency of ABO and Rh D blood groups will assist in the formulation of genetic counseling policies.
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