Abstract
Objective To understand the distribution and drug resistance of clinical pathogenic bacteria in 2012 and provide basis for clinical treatment and hospital infection control. Methods The 3387 strains of pathogenic bacteria isolated were analyzed by WHONET 5. 6 software. Results Gram negative bacilli accounted for 62. 0%（ 2101/3387 ）,and groam positive cocci accounted for 25. 0%（845/3387）,fungus accounted for 13. 0%（441/3387）,respecctively. The top five of pathogen infection were Escherichia coli,Klebsiella pneumoniae,Pseudomonas aeruginosa,Candida albicans,Staphy-lococcus aureus. Methicillin-resistant Staphylococcus aureus（ MRSA）and coagulase negative Staphylo-coccus（ MRCNS）accounted for 14. 6% and 63. 4%,respecctively. No staphylococcal strain was interme-diate or resistant to vancomycin. Two strains of Enterococcus spp. were intermediate to vancomycin （ VIE）. The prevalence of ESBLs producing strains was 60. 5%in Escherichia coli and 31. 3%in Kleb-siella pneumoniae. Conclusions Gram negative bacilli are still the major isolates and multi-drug resistant bacteria infection is serious in our hospital. Clinical doctors should strictly control the use of antibiotics and reduce the outbreak of resistant strains. Key words: Pathogenic bacteria; Distribution ; Drug resistance ; Antimicrobial agents
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