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Abstract
We present a method, termed distributed scanning OCT (DSOCT), which reduces the effects of patient motion on corneal biometry utilizing current-generation clinically available spectral domain optical coherence tomography (SDOCT) systems. We first performed a pilot study of the power spectrum of normal patient axial eye motion based on repeated (M-mode) SDOCT. Using DSOCT to reduce the effects of patient motion, we conducted a preliminary patient study comparing the measured anterior and posterior corneal curvatures and the calculated corneal power to both corneal topography and Scheimpflug photography in normal subjects. The repeatability for the measured radius of curvature of both anterior and posterior surfaces as well as calculated corneal refractive power using DSOCT was comparable to those of both topography and Scheimpflug photography.
Highlights
IntroductionPlacido ring-based corneal topography provides accurate values for the anterior surface of the cornea and calculates total corneal power under the assumption of a constant ratio between anterior and posterior corneal surface radii of curvature [1,2]
For central corneal thicknesses (CCT) and optical distortion correction of optical coherence tomography (OCT) images we used a value for the group refractive index of cornea which we reported in a previous study [13]
Utilizing an spectral domain optical coherence tomography (SDOCT) system that is clinically available, we have developed a technique, termed distributed scanning OCT (DSOCT), which reduces the effects of patient motion in corneal tomographic data for the generation of clinically relevant corneal biometric information
Summary
Placido ring-based corneal topography provides accurate values for the anterior surface of the cornea and calculates total corneal power under the assumption of a constant ratio between anterior and posterior corneal surface radii of curvature [1,2]. This power calculation is compromised when the ratio between surfaces may no longer be considered constant, such as in subjects who have undergone laser refractive surgery (e.g. LASIK, PRK) [3]. Unavoidable patient motion during the time required for conventional OCT imaging may overwhelm the elevation accuracy required for clinically significant corneal curvature or refractive power calculations
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