Abstract

Cancer related death is caused by population aging and stress of unemployment. The absence of cancer in the Eskimos upon his arrival in the Arctic, but a subsequent increase in the incidence of the disease as closer contact with Western civilization is known. Molecular pathogenesis of inhibitory antagonism and disorder in neural phase coordination of reentry, based on a rejection-related distress of unemployment, may lead to the inflammation-induced carcinogenesis. Unemployment leading to cancer pandemic may cause the decay of Western Civilization. Keywords: Rejection-related distress, Lesion of reentry, Inhibitory antagonism, Genetic polymorphisms, The inflammation-drived carcinogenesis, apoptosis-autophagy dichotomy, the NF-KB-IL-6-Stat3 cascade

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