Abstract
The relative stereochemistry of the two acyclic carbons separated by a single bond was determined from three-bond homo- and heteronuclear coupling constants. The analysis of data was based on a purely qualitative interpretation of the Karplus relationships. The methodology presented could resolve acyclic diastereoisomers if adequate sets of three-bond coupling constants can be measured. Copyright © 1999 John Wiley & Sons, Ltd.
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