Distinguish Thyroid Malignant from Benign Alterations using Neutron Activation Analysis of Trace Element Contents in Nodular Tissue

Abstract

Thyroid benign (TBN) and malignant (TMN) nodules are a common thyroid lesion. The differentiation of TMN often remains a clinical challenge and further improvements of TMN diagnostic accuracy are warranted. The aim of present study was to evaluate possibilities of using differences in trace elements (TEs) contents in nodular tissue for diagnosis of thyroid malignancy.