Distinction of Structural Isomers of Benzenediamin and Difluorobenzene by Means of Chirped Femtosecond Laser Ionization Mass Spectrometry

Abstract

Abstract Structural isomers of disubstituted benzenes are difficult to distinguish with most mass spectrometric methods. Consequently, conventional concepts for the distinction of isomers are based on coupling mass spectrometry with a chromatographic method. As an alternative approach, we propose the combination of femtosecond laser ionization with time-of-flight mass spectrometry (fs-LIMS). The possibility of systematic tailoring of fs-laser pulse shapes opens access to a multidimensional analytical technique capable of distinguishing structural isomers of the title molecules.