Distinct indexes of immunological reactivity in surgical alteration of ORL organs

Abstract

The data are provided on applications of optical radiation at various spectral ranges in the treatment of disorders of ORL organs. Some issues of pathophysiological and immune changes of nasal mucosa in response to surgical alteration are considered for the early postoperative period. In order to increase efficiency of postoperative rehabilitation in the patients subjected to rhinosurgical interventions, we have used low-frequency ultrasonic cavitation in combination with photochromotherapy in complex treatment schedules. Assessment of clinical and immunological effects of this treatment was performed as based on the study of clinical and functional pattern at the early stages of postoperative period and stabilization of the cytokine profile. In general, an opportunity of using optical radiation at different wavelength was confirmed, as shown by studies of physical characteristics of light irradiation, explaining the mechanisms of action on the damaged mucous membrane, to apply inflammatory response to surgical trauma and restore immunological abnormalities. The work was carried out in order to draw attention to the non-drug methods of early rehabilitation of persons subjected to rhinosurgical interventions.