Abstract
Distinct Ecologically Relevant Strains of<i>Anaplasma phagocytophilum</i>
Highlights
Our recent data examining A. phagocytophilum in western North America show at least 2 phenotypes: strains originating from sciurids and strains from woodrats
We showed that chipmunks were competent reservoirs for A. phagocytophilum through exposure in the field, successful inoculation with strain MRK, and transmission through Ixodes pacificus to mice
Blood smears showed A. phagocytophilum morulae in neutrophils, and she was PCR positive on day 13 (Ct 37). Infection from this chipmunk strain was indistinguishable from that induced when human-origin A. phagocytophilum was inoculated into this horse
Summary
In: Diseases of domestic animals in Australia. Distinct Ecologically Relevant Strains of Anaplasma phagocytophilum In Europe, A. phagocytophilum infects livestock, rodents, and humans, with some species such as European cattle showing severe disease and high antibody prevalence. Experimental infection of cattle with California equine– origin strain MRK failed to induce disease or marked rickettsemia (1).
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