Distinct dorsal and ventral streams for binocular rivalry dominance and suppression revealed by magnetoencephalography.

Abstract

Binocular rivalry is an example of bistable visual perception extensively examined in neuroimaging. Magnetoencephalography can track brain responses to phasic visual stimulations of predetermined frequency and phase to advance our understanding of perceptual dominance and suppression in binocular rivalry. We used left and right eye stimuli that flickered at two tagging frequencies to track their respective oscillatory cortical evoked responses. We computed time-resolved measures of coherence to track brain responses phase locked with stimulus frequencies and with respect to the participants' indications of alternations of visual rivalry they experienced. We compared the brain maps obtained to those from a non-rivalrous control replay condition that used physically changing stimuli to mimic rivalry. We found stronger coherence within a posterior cortical network of visual areas during rivalry dominance compared with rivalry suppression and replay control. This network extended beyond the primary visual cortex to several retinotopic visual areas. Moreover, network coherence with dominant percepts in primary visual cortex peaked at least 50 ms prior to the suppressed percept nadir, consistent with the escape theory of alternations. Individual alternation rates were correlated with the rate of change in dominant evoked peaks, but not for the slope of response to suppressed percepts. Effective connectivity measures revealed that dominant (respectively, suppressed) percepts were expressed in dorsal (respectively ventral) streams. We thus demonstrate that binocular rivalry dominance and suppression engage distinct mechanisms and brain networks. These findings advance neural models of rivalry and may relate to more general aspects of selection and suppression in natural vision.