DISTINCT AND SHARED CONTRIBUTIONS OF DIAGNOSIS AND SYMPTOM DOMAINS TO COGNITIVE PERFORMANCE IN SEVERE MENTAL ILLNESS

Carrie Bearden,Susan Service,Raquel Gur,Ruben Gur,Oscar Mauricio Castano Ramírez,Marfred E Munoz Umanes,Cristian David Vargas Upegui,Sergio Ruiz Sanchez,Claudia Patricia Montoya,Javier Escobar,Tyler Moore,Allison Port,Victor Reus,Carlos Lopez-Jaramillo,Nelson Freimer

doi:10.1016/j.euroneuro.2019.07.078

DISTINCT AND SHARED CONTRIBUTIONS OF DIAGNOSIS AND SYMPTOM DOMAINS TO COGNITIVE PERFORMANCE IN SEVERE MENTAL ILLNESS

Carrie Bearden, Susan Service + Show 13 more

Open Access

https://doi.org/10.1016/j.euroneuro.2019.07.078

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Journal: European Neuropsychopharmacology

Publication Date: Sep 27, 2019

Affiliation: UCLA Health, University of Pennsylvania, University of Dallas, University of Antioquia, Johnson University, Rutgers, The State University of New Jersey, Rutgers Sexual and Reproductive Health and Rights, University of California, San Francisco

#First Episode Of Schizophrenia #MATRICS Consensus Cognitive Battery + Show 8 more

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Abstract

The objective of the study was to examine the cognitive profile of Spanish patients with a first episode of schizophrenia (FESz) and to compare that to the profile of patients with a chronic schizophrenia (CSz) and non-psychiatric (NP) control subjects. The study included 106 FESz, 293 CSz, and 210 NP, assessed with the Spanish version of the MATRICS Consensus Cognitive Battery (MCCB). The MCCB cognitive profile in a Spanish sample of FESz was similar to the cognitive profile of CSz with some discrepancies in select domains. The scores of both patient samples were about 1–2 SD below the scores of non-psychiatric control subjects.

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