Abstract
The aim of this study was to compare the rate of proximal radial artery occlusion (RAO) with Doppler ultrasound between distal and conventional radial access 24h and 30days after a transradial coronary procedure. The use of distal radial access to prevent proximal RAO (PRAO) in the proximal segment at 24h and 30days after a procedure, compared with conventional radial access, is unknown. This was a prospective, comparative, longitudinal, randomized study. A total of 282 patients were randomized to either proximal radial access (n=142) or distal radial access (n=140) to evaluate the superiority of the distal approach in the prevention of PRAO with Doppler ultrasound 24h and 30days after a transradial coronary procedure. In the per protocol analysis, the rates of PRAO at 24h and 30days were 8.4% and 5.6% in the proximal group and 0.7% and 0.7% in the distal group, respectively (24 h: odds ratio [OR]: 12.8; 95% confidence interval [CI]: 1.6 to 100.0; p=0.002; 30days: OR: 8.2; 95%CI: 1.0 to 67.2; p=0.019). In an intention-to-treat analysis, the 24-h and 30-day rates of PRAO were 8.8% and 6.4% for proximal radial access and 1.2% and 0.6% in the distal radial access group (24 h: OR: 7.4; 95%CI: 1.6 to 34.3; p=0.003; 30days: OR: 10.6; 95%CI: 1.3 to 86.4; p=0.007). Distal radial access prevents RAO in the proximal segment at 24h and 30days after the procedure compared with conventional radial access.
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