Distal Functional Group Migration of Unactivated Alkenes with IMDN‐Tf Reagents

Abstract

AbstractThe difunctionalization of alkenes involving 1,5‐functional group migration strategies for the conversion of versatile and readily available olefins into more structurally complex molecules has been greatly studied. However, the vast majority of the reported reactions rely on strongly oxidizing conditions and oxidizing fluoroalkyl radical reagents. In contrast, few reactions with reduced radical reagents have been reported. This work describes a photo / electroredox catalytic condition for difunctional modification of unactivated olefins via a radical process using IMDN‐Tf reagents with broad substrate scope and excellent tolerance.