Abstract
A method of increasing the dissolution rates of some orally administered corticosteroids was investigated. This method involved glass dispersions using dextrose, galactose, and sucrose as the carriers. These dispersions were prepared by the fusion process and were subjected to a modified NP XIII dissolution rate determination. The results revealed a marked increase in the dissolution rate of the corticosteroids contained in the solid dispersions when compared to the dissolution rate of the plain corticosteroid powder. The increase in dissolution rates was attributed to the presence of the corticosteroid in a very fine state of subdivision and to the increased wettability of the corticosteroid powder.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
