Abstract
PREVIOUSLY, we were able to block mixed lymphocyte reactions (MLR) in man using anti-light chain antibody1 but we have been unable to confirm this observation in subsequent studies using other anti-light chain sera. We have now found that MLR in the mouse is unaffected by a variety of anti-immunoglobulin sera but using alloantisera it has become evident that the stimulator cells, but not the responder lymphocytes, can be blocked.
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