Abstract
Sarcoidosis is a chronic granulomatous idiopathic systemic disease. Although the pulmonary involvement is the most common form of the disease, sarcoidosis can affect the airways, determining mucosal nodularity and even bronchostenosis. Gastrointestinal involvement is very rare and it is primarily manifested as gastric sarcoidosis. The diagnosis is based on symptoms, radiological findings and histopathological examination of tissue biopsies. In this work, we describe a case of pulmonary, endobronchial and gastric sarcoidosis in the same patient and discuss the approach to this rare presentation of the disease
Highlights
Sarcoidosis is a chronic granulomatous idiopathic systemic disease
In this work, we describe a case of pulmonary, endobronchial and gastric sarcoidosis in the same patient and discuss the approach to this rare presentation of the disease
A maioria dos pacientes melhora consideravelmente com os corticoides, embora a melhora clínica nem sempre seja acompanhada da resolução das lesões na histopatologia
Summary
Sarcoidosis is a chronic granulomatous idiopathic systemic disease. the pulmonary involvement is the most common form of the disease, sarcoidosis can affect the airways, determining mucosal nodularity and even bronchostenosis. A sarcoidose é uma doença sistêmica de etiologia desconhecida que se caracteriza por inflamação granulomatosa não caseosa que pode afetar qualquer órgão, principalmente os pulmões.[1] A sarcoidose pulmonar é uma das causas mais comuns de doença intersticial pulmonar, sendo o trato respiratório o mais acometido.[2,3] O diagnóstico é baseado nas suspeitas clínica e radiológica e o achado radiológico mais comum é a linfonodomegalia hilar bilateral com infiltrado pulmonar tipicamente de distribuição perivascular.[4] Quando afeta as vias aéreas, a sarcoidose pode determinar a formação de nódulos ou placas associados a eritema e/ou edema de mucosa, estenose brônquica, bron-
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