Abstract
We report a case of disseminated Mycobacterium genavense infection resulting from neutralizing anti–interferon-γ autoantibodies in the patient. We identified M. genavense targeting the hsp65 gene in an aspiration specimen of the lymph node. Adult-onset immunodeficiency caused by neutralizing anti–interferon-γ autoantibodies, in addition to HIV infection, can lead to disseminated nontuberculous mycobacterial infection.
Highlights
Address for correspondence: Giovanni Maurizio Giammanco, Department of Health Promotion Sciences and Mother and Child Care “G. D’Alessandro”, University of Palermo, Via del Vespro, 133 - 90127
We report a case of disseminated Mycobacterium genavense infection resulting from neutralizing anti–interferon-γ autoantibodies in the patient
We identified M. genavense targeting the hsp65 gene in an aspiration specimen of the Emerging Infectious Diseases
Summary
Disseminated Mycobacterium genavense Infection in Patient with Adult-Onset Immunodeficiency We report a case of disseminated Mycobacterium genavense infection resulting from neutralizing anti–interferon-γ autoantibodies in the patient. Adult-onset immunodeficiency caused by neutralizing anti–interferon-γ autoantibodies, in addition to HIV infection, can lead to disseminated nontuberculous mycobacterial infection.
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