Abstract
Histoplasmosis is an infectious disease caused by the dimorphic fungus Histoplasma capsulatum.. The disseminated form is usually found in immunocompromised patients. A 53 year-old man, renal transplant recipient, was admitted with fever, dyspnea, productive cough, adynamia and weight loss. He was septic, but hemodynamically stable. The tracheal aspirate found intracellular fungi and the peripheral blood exam was compatible with histoplasmosis. The patient presented a progressive worsening of respiratory pattern and needed mechanical ventilation, vasoactive drugs and hemodialysis. A large spectrum antimicrobial therapy was started, including amphotericin B, but the patient died. Keyword: Disseminated histoplasmosis. Kidney transplantation. Immunosuppression DOI: http://dx.doi.org/10.3329/jom.v12i2.7125 JOM 2011; 12(2): 163-165
Highlights
Histoplasmosis is an infectious disease caused by the dimorphic fungus Histoplasma capsulatum, which is endemic in Latin America and is characterized by a broad spectrum of clinical manifestations, from asymptomatic cases to disseminated form, affecting different organs and systems
We report the case of a kidney transplant recipient with Disseminated histoplasmosis (DH) with fatal outcome
DH is an opportunistic infection commonly found in AIDS patients, but it is rarely seen in solid organ transplant recipients
Summary
Introduction: Histoplasmosis is an infectious disease caused by the dimorphic fungus Histoplasma capsulatum, which is endemic in Latin America and is characterized by a broad spectrum of clinical manifestations, from asymptomatic cases to disseminated form, affecting different organs and systems. We report the case of a kidney transplant recipient with DH with fatal outcome. Case Report: A 53 year-old man, from Paracuru (State of Ceará, Brazil), was admitted with complaints of high degree fever (38-39oC), productive cough, adynamia, anorexia and weight loss for 15 days.
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
