Abstract
Plateletpheresis is a crucial step for the blood donation and clinical diagnosis. Herein we demonstrate a method to conduct plateletpheresis using acoustofluidic technology in a disposable device that is fabricated solely by a plastic material with precise simulated modeling using low-cost technic. In this device, a quarter wavelength resonator is utilized in order to serve the top layer as the 'tracking wall.' With this device, over 87% RBC removal and platelet recovery rate are achieved at 20 mL/min flow rate with undiluted whole human blood while the function of the platelets is still retained and better than conventional plateletpheresis method. Conclusively, this disposable device synthesizes the high efficiency, high throughput and high biocompatibility which is suitable as the substitute of the current plateletpheresis equipment.
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