Dispersion curve calculation in viscoelastic tissue-mimicking materials using non-parametric, parametric, and high-resolution methods

Abstract

Ultrasound shear wave elastography is a modality used for noninvasive, quantitative evaluation of soft tissue mechanical properties. A common way of exploring the tissue viscoelasticity is through analyzing the shear wave velocity dispersion curves. The variation of phase velocity with frequency or wavelength is called the dispersion curve. An increase of the available spectrum to be used for phase velocity estimation is meaningful for a tissue dispersion analysis in vivo. A number of available methods for dispersion relation estimation exist which can give diffuse results due the presence of noise in the measured data. In this work we compare six selected methods used for dispersion curve calculation in viscoelastic materials. Non-parametric, parametric and high-resolution methods were examined and compared. We tested selected methods on digital phantom data created using finite-difference-based method in tissue-mimicking viscoelastic media as well as on the experimental custom tissue-mimicking phantoms. In addition, we evaluated the algorithms with different levels of added white Gaussian noise to the shear wave particle velocity from numerical phantoms. Tests conducted showed that more advanced methods can offer better frequency resolution, and less variance than the fast Fourier transform. In addition, the non-parametric Blackman-Tukey approach exhibits similar performance and can be interchangeably used for shear wave phase velocity dispersion curves calculation.