Abstract
Objective To utilize publicly reported, state-level data to identify factors associated with the frequency of cases, tests, and mortality in the USA. Materials and methods Retrospective study using publicly reported data collected included the number of COVID-19 cases, tests and mortality from March 14th through April 30th. Publicly available state-level data was collected which included: demographics comorbidities, state characteristics and environmental factors. Univariate and multivariate regression analyses were performed to identify the significantly associated factors with percent mortality, case and testing frequency. All analyses were state-level analyses and not patient-level analyses. Results A total of 1,090,500 COVID-19 cases were reported during the study period. The calculated case and testing frequency were 3332 and 19,193 per 1,000,000 patients. There were 63,642 deaths during this period which resulted in a mortality of 5.8%. Factors including to but not limited to population density (beta coefficient 7.5, p < .01), transportation volume (beta coefficient 0.1, p < .01), tourism index (beta coefficient −0.1, p = .02) and older age (beta coefficient 0.2, p = .01) are associated with case frequency and percent mortality. Conclusions There were wide variations in testing and case frequencies of COVID-19 among different states in the US. States with higher population density had a higher case and testing rate. States with larger population of elderly and higher tourism had a higher mortality. Key messages There were wide variations in testing and case frequencies of COVID-19 among different states in the USA. States with higher population density had a higher case and testing rate. States with larger population of elderly and higher tourism had a higher mortality.
Highlights
The coronavirus disease 2019 (COVID-19) has spread worldwide after its onset in Wuhan, China, reaching over three million cases[1]
COVID-19 Cases, Testing, and Mortality A total of 1,090,500 COVID-19 cases were reported in the study period
This resulted in a case frequency of approximately 3,332 per 1,000,000 patients (3.3%)
Summary
The coronavirus disease 2019 (COVID-19) has spread worldwide after its onset in Wuhan, China, reaching over three million cases[1]. In the United States (US), over seven million tests have been performed with over one million tests resulting positive. This disease has resulted in over 70,000 deaths in the US and a case fatality rate at approximately 6.2%. Factors mediating the differences in case frequency and testing frequency between the states in the US have not been formally assessed. The aim of this study is to use publicly available, state-level data to determine the factors associated with COVID-19 percent mortality and case and testing frequency
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