Disparities in cancer clinical trials information-seeking: Findings from the National Cancer Institute’s Cancer Information Service

Abstract

ObjectiveTo better understand cancer clinical trials (CCT) information-seeking, a necessary precursor to patient and provider engagement with CCT. MethodsData from the National Cancer Institute’s Cancer Information Service (CIS) were used to examine CCT information-seeking patterns over a 5-year period. Descriptive and logistic regression analyses were conducted to examine characteristics of CIS inquiries and their associations with having a CCT discussion. ResultsBetween September 2018 – August 2023, 117,016 CIS inquiries originated from cancer survivors, caregivers, health professionals, and the general public; 27.5 % of these inquiries included a CCT discussion (n = 32,160). Among CCT discussions, 35.5 % originated from survivors, 53.5 % from caregivers, 6.1 % from the public, and 4.9 % from health professionals. Inquiries in Spanish had lower odds of a CCT discussion (OR=.26, [.25–.28]), whereas inquiries emanating from the CIS instant messaging (OR=2.29, [2.22–2.37]) and email (OR=1.24, [1.18–1.30]) platforms were associated with higher odds of discussing CCT compared to the telephone. Individuals who were male, younger, insured, and had higher income and education had significantly higher odds of a CCT discussion while those who were non-Hispanic Black and living in rural locales had significantly lower odds. ConclusionsDisparities in CCT information-seeking may contribute to downstream CCT participation. Practice ImplicationsQuality, language-concordant health information is needed to enable equitable awareness of – and ultimately engagement in – CCT.