Abstract

Puberty is a complex developmental process that culminates in sexual-maturity. This transitional period begins in late childhood and is characterized by maturation of the hypothalamic—pituitarygonadal axis, the appearance of secondary sexual characteristics, acceleration of growth, and ultimately the capacity for fertility. Significant endocrinologic changes accompany these developmental events. This chapter reviews the physiologic changes of normal puberty and examines the causes of precocious and delayed sexual maturation.KeywordsLuteinizing HormonePubertal DevelopmentPrecocious PubertyGnRH NeuronGonadal DysgenesisThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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