Abstract
This chapter studies the distribution, function, and metabolic regulation of calcium, phosphate, and magnesium in health. It discusses the disorders which cause an alteration in their plasma concentrations, together with their clinical presentation and laboratory investigations and management. Disorders of calcium homeostasis present as either abnormally high plasma calcium or hypercalcaemia, or abnormally low plasma calcium or hypocalcaemia. Meanwhile, disorders of phosphate homeostasis cause hyperphosphataemia or hypophosphataemia. Finally, disorders of magnesium homeostasis can cause either hypermagnesaemia or hypomagnesaemia. Biochemical tests can be used to diagnose disorders of calcium, phosphate, and magnesium homeostasis, and to identify their causes. The chapter then considers the clinical value of bone markers in metabolic bone disease. The major metabolic diseases affecting the bone are osteoporosis, osteomalacia, and Paget's disease.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
