Abstract
The aim of this study was to defne disintegrating perineal disease (DPD) and to determine whether the fulminating nature of the condition could be explained by urine and perineal swab microbiology or perineal histology. A retrospective study that included 12 male patients with urethral strictures and DPD was performed. DPD was defned as a chronic, destructive, purulent perineal infammation with multiple fstulae or sinuses of the perineum, scrotum or penoscrotal area, which continued for more than six weeks despite a patent urethra after direct vision internal urethrotomy (DVIU) or urinary diversion by means of suprapubic cystostomy. The median patient age was 43.5 years (range of 22-68 years). The patients all tested positive for human immunodefciency virus (HIV) infection. Their mean CD4 count was 340 cells/mm3 (range of 244-1 252 cells/mm3). Histology of the fstula tracts showed non-specifc infammation in 8 patients (66.7%), tuberculosis in 2 (16.7%), hydradenitis suppurativa in one (8.3), and squamous ...
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