Abstract
Visual evoked potentials (VEP) and brain stem acoustic evoked potentials (BAEP) were studied in eight children with tuberous sclerosis (four boys and four girls, average age 4.5 years) comparing them with a control group of 21 healthy children (ten boys and 11 girls). The patients had an increased average latency of VEP (IV component or P2; p < .01694) and BAEP (right V wave = p < .001145; left V wave = p < 013792; right I-V interpeak = p < .000543; left I-V interpeak ? p < .009854). Impaired responses were common in both VEP (80%) and BAEP (85%). In addition, altered BAEP were also present in patients without subtentorial structural abnormalities. Evoked potentials serve as a sensitive test for early diagnosis of tuberous sclerosis.
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