Abstract

Diseases of the circulatory system are the main cause of death in the working-age population. The study of the incidence of diseases of the circulatory system of the population of working age in the Russian Federation at the regional level is an urgent task, which is hampered by the lack of statistical information on the incidence of this age group of the population. Objective. To study regional features and dynamics of incidence rates of diseases of the circulatory system in the working-age population of the Central Federal District in 2014–2020. Materials and methods. We conducted a continuous retrospective study based on statistics on disease incidence in the population of the Russian Federation published by the Russian Ministry of Health and the Central Research Institute of Health Care Organization and Informatization. We estimated incidence and prevalence rates of diseases of the circulatory system, including ischemic heart diseases, in the working-age population in 2014–2020 and calculated their long-term averages, standard deviations (σ) and the coefficient of variation (Сv). The Shapiro-Wilk test was used to check if the continuous variables followed a normal distribution, and the Mann-Whitney test was used to assess the differences between the rates observed in the constituent entities of Russia. Results. For the first time, incidence and prevalence rates of diseases of the circulatory system, including ischemic heart diseases, were analyzed in the adult population of working age in the subjects of the Central Federal District. In most parts of the District, we observed an increase in the incidence rates and their statistically significant differences from similar all-Russian indicators for 2014–2019. Changes in the incidence during the spread of the novel coronavirus disease (COVID-19) within the District were multidirectional. Yet, in most regions of the District, we established a statistical difference between the analyzed indicators for the years 2014–2019 and 2020. Conclusion. Incidence and prevalence rates of diseases of the circulatory system, including the ischemic heart disease, in the adult population of working age in the subjects of the Central Federal District are characterized by pronounced regional features, thus prioritizing further epidemiological studies aimed at establishing their causes and risk factors.

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