Abstract
This historical sociological case study examines the emergence and institutionalization of public health transnationalism on the US–Mexico border in the 1940s, shedding light on actors, mechanisms, and processes that preceded the enactment of the World Health Organization. Though the United States instigated the border's first cross-border public health project and provided financing and professional leadership, cooperation took root through transboundary brokerage and associational activities. The Pan American Sanitary Bureau brokered networks and the US–Mexico Border Public Health Association constructed a sense of community, creating a durable, though unequal, arena for public health cooperation still active today.
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