Abstract
In this review from literature appearing over about the past 5 years, we focus on selected selenide reports and related chemistry; we aimed for a digestible, relevant, review intended to be usefully interconnected within the realm of fluorescence and selenium chemistry. Tellurium is mentioned where relevant. Topics include selenium in physics and surfaces, nanoscience, sensing and fluorescence, quantum dots and nanoparticles, Au and oxide nanoparticles quantum dot based, coatings and catalyst poisons, thin film, and aspects of solar energy conversion. Chemosensing is covered, whether small molecule or nanoparticle based, relating to metal ion analytes, H2S, as well as analyte sulfane (biothiols—including glutathione). We cover recent reports of probing and fluorescence when they deal with redox biology aspects. Selenium in therapeutics, medicinal chemistry and skeleton cores is covered. Selenium serves as a constituent for some small molecule sensors and probes. Typically, the selenium is part of the reactive, or active site of the probe; in other cases, it is featured as the analyte, either as a reduced or oxidized form of selenium. Free radicals and ROS are also mentioned; aggregation strategies are treated in some places. Also, the relationship between reduced selenium and oxidized selenium is developed.
Highlights
Selenium has experienced an upsurge in research interest in the past 5 years, especially in the somewhat related realms of biology, sensing, and medicinal chemistry
We focus on selenium as a constituent of small molecule sensors
Recent reports involving glutathione (GSH) as an analyte include a paper by Sivasankaran et al who designed a novel green synthesis method containing carbon dots (CDs) which were used as a reduced glutathione (GSH) fluorescence probe
Summary
Selenium has experienced an upsurge in research interest in the past 5 years, especially in the somewhat related realms of biology, sensing, and medicinal chemistry. The selenium is part of the reactive or active site of the probe; in other cases, it is featured as the analyte, either as a reduced or oxidized form of selenium. It seems that the Se–S bond is receiving more research attention now. MnSOD Ala–9Val is an antioxidant responsible for conversion of the superoxide radical into hydrogen peroxide; GPx1 Pro198Leu is an antioxidant responsible for conversion of hydrogen peroxide into water Polymorphisms of these enzymes are much less catalytically active. There are other important biological and environmental findings in the recent 5 years (see references [3,4,5,6,7,8,9,10,11,12,13])
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
