Abstract
Severe limbal stem cell deficiency is a challenging management problem. Standard approaches to remove the abnormal epithelium with superficial keratectomy or keratoplasty fail in all cases of severe limbal stem cell deficiency. The failure results because the underlying abnormality, that being an inadequate supply of normal healthy epithelium to the ocular surface, has not been addressed. Recently, limbal stem cell transplantation has been devised to address this problem. For unilateral disease, conjunctival limbal autograft procedure is a highly successful procedure in which conjunctiva and limbus from the fellow eye are transplanted to the diseased eye.1 The success rate is high, because rejection is not an issue. For bilateral disease, the source of stem cells can either be a relative (living related conjunctival limbal allograft) or a cadaver (keratolimbal allograft).2
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