Discussion on the Correlation between Clinical Typing of Covid-19 Patients and Risk Factors and Peripheral Red Blood Cell Parameters

Abstract

To investigate the correlation between clinical typing of coronavirus disease-19 patients and risk factors (age, sex, underlying disease), hematocrit (packed-cell volume), mean erythrocyte volume, standard deviation of erythrocyte volume distribution width, variation coefficient of erythrocyte distribution width and other peripheral erythrocyte parameters. Retrospective analysis from January 2020 to March 2020 were coronavirus disease-19, 82 cases of patients, according to the hospital condition grading assessment can be divided into normal group and the normal group (including heavy type and critically ill patients), using R*C chi-square statistics of gender and the presence of basic diseases, the binary classification Logistic regression analysis statistic average age, red blood cells deposited (packed-cell volume), red blood cell volume, red blood cell volume distribution width standard deviation, red blood cell distribution width variation coefficient, determine the correlation between. There were differences in age and presence of underlying diseases (p<0.05); There were no significant differences in hematocrit (packed-cell volume) or mean erythrocyte volume between the normal and non-normal groups (including severe and critically ill patients) (p<0.05); There were differences in standard deviation and variation coefficient of erythrocyte distribution width between the normal group and the non-normal group (including severe and critical patients) (p<0.05). In coronavirus disease-19 patients, increased age, accompanied by underlying disease, decreased standard deviation of red blood cell volume distribution width, and increased variation coefficient of red blood cell distribution width are correlated with the severity of the disease to a certain extent, and can be used as one of the predictive indicators of the severity of the disease in coronavirus disease-19 patients.