Discussion on relationship between gynecological laparoscopic postoperative cognitive function and the sedation depth of intravenous inhalational anesthesia

Abstract

Objective To discuss the relationship between gynecological laparoscopic postoperative cognitive function and the sedation depth of intravenous inhalational anesthesia. Methods 105 cases of gynecological laparoscopic surgery in our hospital from February 2014 to April 2016 were chosen, all patients received sevoflurane inhalation, remifentanil intravenous injection, rocuronium intermittent intravenous injection. Maintained different levels of BIS by regulating the remifentanil infusion speed. All patients were divided into group A, group B, and group C according to different depth of anesthesia, BIS value was 30-40 in group A, 40-50 in group B, 50-60 in group C. Assessed cognitive function with mini-mental state examination (MMSE) before and after anesthesia, and recorded the completion time of trailmaking test (TMT). Results There were no statistically significant differences in MMSE scores before and after operation among the three groups (P>0.05). The descend range of TMT time in group B [(33.1±14.9)s] was significantly greater than those in other two groups [(37.2±15.7)s, (36.3±12.8)s], with statistically significant differences (P 0.05). Conclusions In gynecological laparoscopic surgery, it can reduce the impact on postoperative cognitive function in patients, at the same time ensure good anesthetic effect to control the sedation depth of intravenous inhalational anesthesia at BIS 40-50, promoting the smooth postoperative recovery. Key words: Gynecological laparoscopic surgery; Intravenous inhalational anesthesia; Anesthesia depth; Cognitive function