Abstract
It is written in the PhD abstract by Kassis (2008) that independent research on policosanols was not able to replicate cholesterol reductions reported by Cuban laboratories, and that no independent study to date has examined the cholesterol-lowering effect of original sugar cane policosanols in humans (Kassis 2008). However, in the year 2000, results of a multicenter controlled double blind randomized trial in 113 patients with hypercholesterolemia were published, where effectiveness of original sugar cane policosanol was compared with that of bezafibrate. It was shown that lipid-lowering effect of policosanol in a daily dose 10 mg was superior to that of bezafibrate in a daily dose 400 mg (Nikitin et al. 2000). The study was performed at the I.M. Sechenov Moscow Medical Academy, Moscow, Russia, and other renowned clinical centers, so that there are no grounds to disregard these data. Higher lipid-lowering effectiveness of sugar cane policosanol in patients with hyperlipidemia was reported also in comparison with statins in a double blind randomized study from Chile (Prat et al. 1999).
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