Abstract

Rats were trained to escape from shock in a T-maze. Repeated training sessions were administered with a right turn required after electroconvulsive shock (ECS) and a left turn after no treatment. Results were as follows: (1) Postictal state was readily discriminated 2-10 min after ECS. (2) Discriminability attenuated by 60 min and was absent 2-7 days after ECS. (3) Severe footshock just prior to ECS did not alter ECS discriminability. (4) No simple interchangeability between cueing effects of drugs and ECS was found. The postictal state is discriminated as rapidly as are centrally acting drugs. Similar mechanisms may be involved.

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