Abstract

Light chain associated proximal tubulopathy is a rare form of Monoclonal Gammopathy-related kidney disease. Common causes include myeloma, monoclonal gammopathy of renal significance and B-cell lymphomas.1,2 Accumulation of intracytoplasmic crystalline inclusions, composed of abnormal monoclonal light chains, cause chronic damage to proximal tubules. These light chains are resistant to enzymatic breakdown.2,3 We present a case of a 61-year-old man with progressive decline in renal function without proteinuria.

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