Directed Manganation of Functionalized Arenes and Heterocycles Using tmp2Mn⋅2 MgCl2⋅4 LiCl

Abstract

Convenient metalation procedures: Directed manganation using tmp2Mn⋅2 MgCl2⋅4 LiCl leads to the corresponding diorganomanganese reagents in high yields at 0–25 °C. Remarkably, a number of functionalities as well as sensitive heterocycles are tolerated in this metalation procedure (see scheme). The organomanganese species react with a great variety of electrophiles and undergo efficient oxidative amination reactions. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.