Abstract
Implants of slow-release polymer Elvax-40 containing purified sea star factor (SSF) and rabbit T cell lymphokines were sutured to the coelomic wall of the distal arms of the sea star Asterias forbesi . Scanning electron microscopic evaluation of the pellet surface demonstrated adherence and spreading of coelomocytes over SSF- or lymphokine-containing pellets examined from 6 to 48 hours after implantation. These observations indicate that purified SSF and rabbit lymphokines demonstrate cross-phylum biological mimicry, implying a phylogenetic link between vertebrate and invertebrate cell communication mechanisms in immunoprotective functions.
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