Abstract

A device has been constructed and tested which provides immediate readout of bone mineral content and bone width from absorptiometric scans with low-energy radionuclides (such as 125I). The basis of this analog system is a logarithmic converter-integrator coupled with a precision linear ratemeter. The system provided accurate and reliable results on standards and ashed bone sections. The standard deviation for measurements on standards over a year was about 1 per cent; the standard deviation for the residuals about the regression line predicting the ash weight of bone sections was about 1·5 per cent, but part of this appeared due to variability in the bone sections rather than due to limitations of the instrumentation. Clinical measurements were made on about 100 patients with the direct readout system, and these were highly correlated with the results from digital scan data on the same patients. The direct readout system has been used successfully in field studies and surveys as well as for clinical observations. Such an analog system has several advantages over previously-used digital handling of scan data, including lower operational and equipment costs, greater mobility, and immediate availability of results.

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