Abstract

To describe our single-center experience of mechanical thrombectomy (MTE) via a direct carotid puncture (DCP) with regard to indication, time metrics, procedural details, as well as safety and efficacy aspects. DCP thrombectomy cases performed at our center were retrospectively identified from a prospectively maintained institutional MTE database. Various patient (age, sex, stroke cause, comorbidities), clinical (NIHSS, mRS), imaging (occlusion site, ASPECT score), procedural (indication for DCP, time from DCP to reperfusion, materials used, technical nuances), and outcome data (NIHSS, mRS) were tabulated. Among 715 anterior circulation MTEs, 12 DCP-MTEs were identified and analyzed. Nine were left-sided M1 occlusions, one right-sided M1 occlusion, and two right-sided M2 occlusions. DCP was successfully carried out in 91.7%; TICI 2b/3-recanalization was achieved in 83.3% via direct lesional aspiration and/or stent-retrieval techniques. Median time from DCP to reperfusion was 23 min. Indications included futile transfemoral catheterization attempts of the cervical target vessels as well as iliac occlusive disease. Neck hematoma occurred in 2 patients, none of which required further therapy. MTE via DCP in these highly selected patients was reasonably safe, fast, and efficient. It thus represents a valuable technical extension of MTE, especially in patients with difficult access.

Highlights

  • Outcomes in the ROADSTER 2 Study of Transcarotid Artery Revascularization in Patients With Significant Carotid Artery Disease

  • Commentary: I mentioned in a review of an article in last month’s JVS Vantage Point November 2020 issue that I believe transcarotid revascularization (TCAR) will replace carotid endarterectomy (CEA) for most patients in the near future

  • As with CEA, patients must be carefully selected for TCAR

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Summary

VASCULAR VANTAGE POINT

Study design: A prospective, open label, single-arm, multicenter, postapproval registry study was performed from 2015 to 2019. Key findings: A total of 632 patients at 43 sites considered at high risk of complications from carotid endarterectomy (CEA; anatomic factors, 44%; physiologic factors, 32%; both, 24%) with symptomatic stenosis $50% or asymptomatic stenosis $80% underwent transcarotid revascularization (TCAR). 81% were TCAR naive before study initiation. One quarter of the patients were symptomatic. The technical success rate was 99.7% for all cases and 98% for the per-protocol patients. The composite 30-day stroke/death rate was 2.3% and the stroke/ death/myocardial infarction rate was 3.2%. In the per-protocol population, the composite 30-day stroke/death rate was 0.8% and the stroke/ death/myocardial infarction rate was 1.7%

Conclusion
Vascular Access Technique for Mechanical
Tissue Disorders
Findings
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