Abstract
Direct cardiac magnetic resonance elastography (MRE) based on harmonically oscillating tissue interfaces is introduced. This method exploits cardiac triggered cine imaging synchronized to extrinsic harmonic motion of 22.83Hz frequency for displaying oscillatory tissue deformations in the magnitude image. Oscillations are analyzed by intensity-threshold based image processing for delineating wave amplitude variations over the cardiac cycle. Initial results showed that endocardial wave amplitudes during systole (0.13±0.07)mm were significantly lower than during diastole (0.34±0.14)mm. Wave amplitudes were found to decrease (117 ± 40)ms before myocardial contraction and to increase (75±31)ms prior to myocardial relaxation. Not requiring extra motionencoding gradients the introduced method enables short-TR vibration imaging and therewith improves the time resolution in cardiac MRE.
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