Abstract
Many implantable biomedical devices suffer from post-operative infections. To effectively treat post-operative infections, prevention of biofilm and tissue integrations needs to be addressed simultaneously. In this manuscript we report the direct laser patterning of SAMs on Co-Cr alloy that could serve as a platform for multi therapeutic delivery. A sapphire femtosecond pulsed laser was used to etch the SAMs on the Co-Cr alloy. Atomic force microscope (AFM) showed the surface topography before and after the laser etches as well as determined the diameter of laser etches. The experimental value of the diameter of the laser etch closely matched the theoretical predicted values.
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