Abstract

The laboratory diagnosis of specific viral infections depends on isolation of the causative agent(s) and/or demonstration of a significant increase in serum antibody. Recently, immunofluorescent techniques have provided a rapid and sensitive method for the diagnosis and study of several respiratory virus infections [1-6]. Respiratory syncytial (RS) virus is a major cause of respiratory illness in infants and children [7-10]. Gray et al. [11] and McQuillin and Gardner [12, 13] have successfully introduced the indirect immunofluorescent technique for the rapid diagnosis of infections with RS virus. The purpose of this investigation was to evaluate the specificity and sensitivity of a direct immunofluorescent method for the clin-

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