Direct Hydrolysis of O,O′-Dibenzoyltartaric Anhydride - An Alternative Method for Manufacture of the same Acid: Tartaric Acid and Its O-Acyl Derivatives. Part 9

Abstract

Efficient, direct, one-pot hydrolysis of O,O′-dibenzoyltartaric anhydride produced via benzoylation of tartaric acid was achieved, whereby a complete and efficient method of manufacturing O,O′-dibenzoyltartaric acid was developed. The process was successfully optimized by using factorial and rotatable designs. The yield was increased from 81 to 95%. The results obtained in the laboratory were then successfully implemented in the pilot-plant-scale process.