Abstract
A new strategy for the synthesis of α-alkylated ketones from secondary alcohols and primary alkenyl alcohols via a tandem transfer hydrogenation/hydrogen autotransfer process was proposed and successfully accomplished. Mechanistic experiments supported that functional groups in bpy ligand are crucial for the transfer hydrogenation and hydrogen autotransfer process. Furthermore, the utilization of the present catalytic system for the gram-scale synthesis of a biologically active compound was presented.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have